Drug to SNP: A Pharmacogenomics Database for Linking Drug Response to SNPs

One of the recent critical issues in linking genetic variation to clinical phenotypes is to apply population genetic analyses to high-throughput genomics data to investigate underlying patterns of variation in the human genome. Especially, relating drug response to genetic variation has been emerging in the field of pharmacogenomics [2] with the combined use of genetics and functional genomics data. Thus, we have constructed a database on Single Nucleotide Polymorphisms(SNPs) that were present within genes which codes drug targets. It provides combined information on drug target proteins (including enzyme, receptor, and agonists/antagonists), genes and SNPs. Especially, this Drug-SNP DB will be helpful for obtaining information on drug response study. Although there are some SNP databases, there exists no database which provides search by a drug name itself as a keyword. Drug-SNP DB server provides users to this convenience of using a drug name directly.